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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STAT4
All Species:
11.52
Human Site:
S721
Identified Species:
31.67
UniProt:
Q14765
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14765
NP_003142.1
748
85941
S721
P
S
D
L
L
P
M
S
P
S
V
Y
A
V
L
Chimpanzee
Pan troglodytes
XP_511505
786
90098
S730
M
S
P
R
T
L
D
S
L
M
Q
F
G
N
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536007
913
103374
S721
P
S
D
L
L
P
M
S
P
S
V
Y
A
V
L
Cat
Felis silvestris
Mouse
Mus musculus
P42228
749
85922
S722
P
S
D
L
L
P
M
S
P
S
A
Y
A
V
L
Rat
Rattus norvegicus
P52631
770
88021
S733
M
S
P
R
T
L
D
S
L
M
Q
F
G
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q6DV79
771
88152
D733
P
M
S
P
R
T
L
D
S
L
M
Q
F
G
N
Frog
Xenopus laevis
Q9PVX8
769
87956
D733
P
M
S
P
R
T
L
D
S
L
M
Q
F
P
G
Zebra Danio
Brachydanio rerio
NP_001004510
667
77275
N641
A
D
G
V
V
P
E
N
P
L
N
F
L
Y
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24151
761
86396
T732
E
N
G
S
T
S
G
T
P
H
H
A
Q
E
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.5
N.A.
79.6
N.A.
94.5
47.1
N.A.
N.A.
47.5
47.5
57.8
N.A.
26.4
N.A.
N.A.
N.A.
Protein Similarity:
100
66.2
N.A.
81.1
N.A.
97.3
66.4
N.A.
N.A.
66.9
67.2
72.3
N.A.
48.3
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
N.A.
100
N.A.
93.3
13.3
N.A.
N.A.
6.6
6.6
13.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
N.A.
100
N.A.
93.3
20
N.A.
N.A.
20
20
40
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
0
0
0
0
12
12
34
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
34
0
0
0
23
23
0
0
0
0
0
0
0
% D
% Glu:
12
0
0
0
0
0
12
0
0
0
0
0
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
34
23
0
0
% F
% Gly:
0
0
23
0
0
0
12
0
0
0
0
0
23
12
12
% G
% His:
0
0
0
0
0
0
0
0
0
12
12
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
34
34
23
23
0
23
34
0
0
12
0
34
% L
% Met:
23
23
0
0
0
0
34
0
0
23
23
0
0
0
0
% M
% Asn:
0
12
0
0
0
0
0
12
0
0
12
0
0
23
34
% N
% Pro:
56
0
23
23
0
45
0
0
56
0
0
0
0
12
12
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
23
23
12
0
0
% Q
% Arg:
0
0
0
23
23
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
56
23
12
0
12
0
56
23
34
0
0
0
0
12
% S
% Thr:
0
0
0
0
34
23
0
12
0
0
0
0
0
0
0
% T
% Val:
0
0
0
12
12
0
0
0
0
0
23
0
0
34
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
34
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _